Trivalent GalNAc-DBCO, CAS [[2765060-22-6]]

Artikelnummer: TGM-T210528
Artikelname: Trivalent GalNAc-DBCO, CAS [[2765060-22-6]]
Artikelnummer: TGM-T210528
Hersteller Artikelnummer: T210528
Alternativnummer: TGM-T210528-1MG,TGM-T210528-5MG,TGM-T210528-10MG,TGM-T210528-25MG,TGM-T210528-50MG,TGM-T210528-100MG
Hersteller: TargetMol
Kategorie: Biochemikalien
Trivalent GalNAc-DBCO is a synthetic ligand composed of three GalNAc units linked to DBCO. Trivalent GalNAc-DBCO undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with azide-containing molecules without the need for copper catalysis. Trivalent GalNAc-DBCO binds specifically to the asialoglycoprotein receptor (ASGPR), thereby directing conjugated molecules into hepatocytes for lysosomal degradation through receptor-mediated endocytosis. Trivalent GalNAc-DBCO is extensively applied in studies of liver-targeted drug delivery, targeted degradation strategies, and hepatocyte-specific molecular engineering.
Molekulargewicht: 1950.18
Reinheit: 96.33%
CAS Nummer: [2765060-22-6]
Formel: C91H144N12O34
Target-Kategorie: Transmembrane Glycoprotein
T210528