KMS99220 is an orally active Keap-1 activator that acts as an Nrf2 inhibitor protein. It enhances Nrf2 nuclear translocation, increases the expression of antioxidant enzymes (such as heme oxygenase-1) and proteasome subunit genes, and alleviates oxidative stress and protein aggregation damage. KMS99220 is applicable for research in Parkinsons disease (PD).
Molekulargewicht:
455.9
CAS Nummer:
[1478585-60-2]
Formel:
C23H25ClF3NO3
Target-Kategorie:
Nrf2
T210562
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