BER-5 is a potent MrgX2 antagonist, demonstrating broad-spectrum antagonistic activity against various MrgX2 agonists. It can inhibit Substance P(SP)-induced degranulation in LAD2 cells and alleviate SP-induced allergic reactions in mice. BER-5 is useful for researching mechanisms related to allergic reactions.
Molekulargewicht:
320.34
CAS Nummer:
[724709-67-5]
Formel:
C20H16O4
Target-Kategorie:
MRGPR|||Interleukin|||Calcium Channel
T210613
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