NLRP3-IN-81, CAS [[2922814-85-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: NLRP3-IN-81, CAS [[2922814-85-3]] Preis auf Anfrage
• Artikelnummer: TGM-T210731
• Hersteller Artikelnummer: T210731
• Alternativnummer: TGM-T210731-10MG,TGM-T210731-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

NLRP3-IN-81 (N102) is an inhibitor capable of crossing the blood-brain barrier, effectively countering NLRP3 inflammasome-dependent pyroptosis with an EC50 of 0.029 µM for Nigericin-induced pyroptosis. It significantly suppresses caspase-1 activation and IL-1beta release that depend on NLRP3. Additionally, NLRP3-IN-81 disrupts the interaction between NLRP3 and the adaptor protein ASC, while inhibiting ASC oligomerization. This compound is applicable in research on pyroptosis-related diseases, such as inflammatory bowel disease and type 2 diabetes.

Produkteigenschaften

• Molekulargewicht: 372.36
• CAS Nummer: [2922814-85-3]
• Formel: C16H15F3N2O3S
• Target-Kategorie: Interleukin|||Pyroptosis|||Caspase|||NOD-like Receptor (NLR)

Bilder

T210731