PRMT5-MTA-IN-4, CAS [[3025838-18-7]] Preis auf Anfrage
Artikelnummer:
TGM-T210750
Hersteller Artikelnummer:
T210750
Alternativnummer:
TGM-T210750-10MG,TGM-T210750-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
PRMT5-MTA-IN-4 (Compound 30) is a potent irreversible inhibitor of protein arginine methyltransferase 5 (PRMT5) with an IC50 of 8 nM. It obstructs arginine methylation, hinders ribosomal RNA processing, and suppresses cell cycle-related protein expression. This compound shows antiproliferative activity in various tumor cell lines, exemplified by an IC50 of 0.3 µM in DLD-1 cells. PRMT5-MTA-IN-4 holds potential for research into hematological malignancies such as acute myeloid leukemia and diffuse large B-cell lymphoma.
Molekulargewicht:
504.94
CAS Nummer:
[3025838-18-7]
Formel:
C26H22ClFN6O2
Target-Kategorie:
Histone Methyltransferase
T210750
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