MJ-26 is an inhibitor targeting Menin, characterized by a high binding affinity (Ki: 0.56 µM) and significant antiproliferative activity. It functions by inhibiting Menin-MLL interaction and promoting the degradation of Menin protein. MJ-26 demonstrates notable antitumor effects against acute myeloid leukemia (AML) and is applicable for AML research.
Target-Kategorie:
Epigenetic Reader Domain
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