CDK6/PIM1-IN-1 hydrochloride, CAS [[2677026-15-0]] Preis auf Anfrage
Artikelnummer:
TGM-T210855
Hersteller Artikelnummer:
T210855
Alternativnummer:
TGM-T210855-10MG,TGM-T210855-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
CDK6/PIM1-IN-1 (Compound 51) hydrochloride is an orally active and potent dual inhibitor of CDK6 and PIM1, with IC50 values of 39 nM and 88 nM, respectively. It also inhibits CDK4 with an IC50 of 3.6 nM. This compound significantly suppresses the proliferation of acute myeloid leukemia (AML) cells, arrests the cell cycle at the G1 phase, and induces apoptosis. CDK6/PIM1-IN-1 hydrochloride demonstrates anti-AML activity.
Molekulargewicht:
510.01
CAS Nummer:
[2677026-15-0]
Formel:
C25H29ClFN9
Target-Kategorie:
Apoptosis|||Pim|||CDK
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