MSK-9 is an allosteric modulator of the P2X4 receptor, exhibiting dual actions of enhancing ion conductivity and delaying receptor desensitization. By stabilizing the receptors open state, MSK-9 utilizes rigid 3-piperidinyl and hydrophobic menthyl substituents. MSK-9 is applicable in research related to multiple sclerosis (MS).
Target-Kategorie:
P2X Receptor
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