MG-3C is a potent inhibitor of matrix metalloproteinase 9 (MMP-9). It selectively targets and kills non-small cell lung cancer (NSCLC) cells harboring the EGFR T790M mutation. By blocking the EGFR/STAT3 signaling pathway, MG-3C induces cell cycle arrest at the G2/M phase, inhibits growth, and triggers apoptosis. This compound shows potential for lung cancer research.
Target-Kategorie:
EGFR|||STAT|||MMP|||Apoptosis
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