BP-198 is a MproPROTAC degrader that enhances the ubiquitination and degradation of Mpro. It exhibits antiviral activity against SARS-CoV-2 with an IC50 of 11.8 µM and demonstrates increased efficacy against drug-resistant viruses.
Target-Kategorie:
Virus Protease|||PROTACs|||SARS-CoV
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