TREM2 agonist-4 (Compound 4a) is a TREM2 agonist with a Kd value of 45.9 µM. It activates the TREM2 downstream signaling pathways and enhances the phagocytic function of microglia. TREM2 agonist-4 is applicable for research into neurodegenerative diseases such as Alzheimers disease.
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