AR antagonist 15, CAS [[1790308-86-9]] Preis auf Anfrage
Artikelnummer:
TGM-T210996
Hersteller Artikelnummer:
T210996
Alternativnummer:
TGM-T210996-10MG,TGM-T210996-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
AR antagonist 15 is an orally active androgen receptor (AR) antagonist with an IC50 of 97 nM for ART787A. It impairs AR nuclear translocation, hinders AR homodimerization, and inhibits AR-regulated gene transcription by competitively binding to the ligand-binding pocket. AR antagonist 15 significantly reduces prostate-specific antigen (PSA) levels and induces apoptosis by decreasing the expression of apoptosis-related proteins. This compound is useful for prostate cancer research.
Molekulargewicht:
346.44
CAS Nummer:
[1790308-86-9]
Formel:
C18H22N2O3S
Target-Kategorie:
Apoptosis|||Androgen Receptor
T210996
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