KL1333 hydrochloride, CAS [[1800406-26-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: KL1333 hydrochloride, CAS [[1800406-26-1]] Preis auf Anfrage
• Artikelnummer: TGM-T211087
• Hersteller Artikelnummer: T211087
• Alternativnummer: TGM-T211087-10MG,TGM-T211087-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

KL1333 hydrochloride is an orally effective NAD+ modulator that acts as a substrate for NAD(P)H: quinone oxidoreductase 1 (NQO1), leading to increased intracellular NAD+ levels through NADH oxidation. Elevated NAD+ subsequently activates SIRT1 and AMPK, which in turn activate PGC-1alpha. KL1333 hydrochloride improves energy metabolism and mitochondrial dysfunction in fibroblasts of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). It also has a protective effect against cisplatin-induced ototoxicity in cultured mouse cochlea.

Produkteigenschaften

• Molekulargewicht: 276.72
• CAS Nummer: [1800406-26-1]
• Formel: C14H13ClN2O2
• Target-Kategorie: Mitochondrial Metabolism|||Reductase

Bilder

T211087