ANT2681 is a potent NDM inhibitor with a Ki value of 0.04 µM for NDM-1. It also inhibits other MBLs such as VIM-1 and IMP-1, with Ki values of 0.63 µM and 3.81 µM, respectively. ANT2681 can be used in combination with Meropenem to suppress infections caused by NDM-producing Enterobacteriaceae.
Molekulargewicht:
435.39
CAS Nummer:
[2270184-16-0]
Formel:
C12H11F2N7O5S2
Target-Kategorie:
Antibacterial
T211170
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