Jun15799 is an inhibitor of the enterovirus 2C protein (EVs 2C), with Ki values of 0.8 µM, 21.1 µM, and 3.0 µM for EV-D68, EV-A71, and CVB3, respectively. It exhibits potent antiviral activity against EV-D68 US/MO/14-18947, EV-A71 Tainan/4643/1998, and CVB3 Nancy cells, with EC50 values of 0.3 µM, 11.4 µM, and 0.3 µM, respectively. Jun15799 is applicable in research related to viral infections such as meningitis, hand, foot, and mouth disease (HFMD), and viral myocarditis.
Target-Kategorie:
Virus Protease
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