NOX5-IN-2 (Compound 17) is a selective inhibitor of NADPH oxidase 5 (NOX5) with an IC50 value of 0.70 µM. It effectively suppresses NOX5-dependent ROS production in freestyle293 cells, exhibiting an EC50 of 1.8 µM. NOX5-IN-2 is useful for researching NOX-related diseases, such as cardiovascular disorders, cancer, and neuroinflammation.
Target-Kategorie:
NADPH|||ROS
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