PROTAC pan-KRAS degrader-1, CAS [[3043908-63-7]] Preis auf Anfrage
Artikelnummer:
TGM-T211239
Hersteller Artikelnummer:
T211239
Alternativnummer:
TGM-T211239-10MG,TGM-T211239-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
PROTACpan-KRAS degrader-1 is a pan-KRAS PROTAC degrader that targets multiple KRAS mutants, including G12D, G12C, G12V, and G13D. It effectively degrades the KRAS mutant (G12D) in AGS cells, with a DC50 of 1.1 nM and a Dmax of 95%. This compound can be used in studies of diseases caused by KRAS mutations or amplifications, particularly in cancers such as breast, bladder, and gastric cancer.
Molekulargewicht:
1192.38
CAS Nummer:
[3043908-63-7]
Formel:
C63H71F2N13O7S
Target-Kategorie:
Ras|||PROTACs
T211239
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