TR antagonist 2, CAS [[1073179-55-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: TR antagonist 2, CAS [[1073179-55-1]] Preis auf Anfrage
• Artikelnummer: TGM-T211252
• Hersteller Artikelnummer: T211252
• Alternativnummer: TGM-T211252-10MG,TGM-T211252-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien

Produktbeschreibung

TR antagonist 2 (Compound 10a) is a competitive inhibitor of thyroid hormone receptors (TRalpha/beta) with an IC50 of 47 nM. It works by competitively binding to the ligand-binding domain of the receptor with triiodothyronine (T3), thereby blocking the formation of the receptor-coactivator complex, inhibiting target gene transcription, and reducing thyroid hormone-mediated metabolic effects. TR antagonist 2 holds potential for research into hyperthyroidism (such as Graves disease) and thyrotoxicosis.

Produkteigenschaften

• Molekulargewicht: 463.41
• CAS Nummer: [1073179-55-1]
• Formel: C21H20F3N5O4
• Target-Kategorie: Thyroid hormone receptor(THR)

Bilder

T211252