dASK1 is a selective CRBN-based PROTAC degrader targeting apoptosis signal-regulating kinase 1 (ASK1). It forms a stable ternary complex with ASK1, facilitating its rapid and sustained degradation via the ubiquitin-proteasome pathway. dASK1 exhibits strong ASK1 degradation capabilities and is applicable for hepatitis research.
Molekulargewicht:
800.77
CAS Nummer:
[3064086-31-0]
Formel:
C38H38F2N10O8
Target-Kategorie:
ASK|||PROTACs
T211263
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