DMU759 is a lysyl-tRNA synthetase 1 (KRS1) inhibitor. It exhibits potent anti-kinetoplastid activity against Trypanosoma cruzi, Trypanosoma brucei, and Leishmania donovani. In mouse models of acute Chagas disease, DMU759 significantly reduces parasitemia. DMU759 is applicable for research on parasitic infections, including Chagas disease.
Molekulargewicht:
327.37
CAS Nummer:
[3052352-22-1]
Formel:
C15H16F3N3S
Target-Kategorie:
Parasite
T211714
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