HV1-IN-2 (Compound 14c) is an inhibitor of human voltage-gated proton channels (HV1) with an IC50 of 2.14 µM. It exhibits potent anticancer activity, showing significant antiproliferative effects on THP-1 and MCF-7 cells. HV1-IN-2 is applicable in cancer research, including studies on colorectal tumors, leukemia, and breast cancer.
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