QNX-10 is a fatty acid synthase (FASN) inhibitor with anticancer properties (IC50 = 0.7 µM). It exhibits potent FASN inhibition and cytotoxicity against colorectal and breast cancer cells. By upregulating the pro-apoptotic protein Bax and downregulating the anti-apoptotic protein Bcl-xL, QNX-10 induces apoptosis and causes cell cycle arrest at the S phase. This compound is utilized for investigating anticancer therapies targeting the FASN enzyme.
Target-Kategorie:
Apoptosis|||Bcl-2 Family|||Fatty Acid Synthase
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