Ranbezolid (RBx7644 free base) is an orally active oxazolidinone antibiotic effective against both Gram-positive and Gram-negative anaerobic bacteria, including Staphylococcus aureus, Staphylococcus epidermidis, and Bacteroides fragilis. It inhibits the 50s ribosomal subunit, with an IC50 value of 17 µM for bacterial ribosomes, and disrupts cell wall and lipid synthesis. Ranbezolid acts as a rapid bactericidal agent, significantly reducing bacterial load, and demonstrates improved cardiovascular safety. It is applicable in the study of antibiotics targeting anaerobic bacteria.
Molekulargewicht:
461.44
CAS Nummer:
[392659-38-0]
Formel:
C21H24FN5O6
Target-Kategorie:
Antibacterial|||Antibiotic
T211882
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