LGT-1 is a PD-L1 ligand. The compound labeled with 18F shows exceptional specificity and uptake in B16-F10 tumor cells and demonstrates high tumor uptake with relatively low liver uptake in mouse models carrying B16-F10 tumors, while maintaining good stability. LGT-1 can be utilized as a radiotracer for PET imaging of tumor PD-L1 expression.
Target-Kategorie:
Others|||PD-1/PD-L1
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