Mrt-5702D is a molecular glue degrader targeting cereblon (CRBN). It forms a ternary complex with CRBN and G3BP2, activating the ubiquitin-proteasome system to degrade G3BP2. Mrt-5702D holds potential for research in G3BP2-related cancers (such as breast cancer and lung cancer) and neurodegenerative diseases.
Target-Kategorie:
Molecular Glues|||PROTACs
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