HPK1-IN-61 (Compound 1) serves as an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with a Ki of 0.4 nM, and also inhibits Abl with an IC50 of less than 0.51 nM. Additionally, HPK1-IN-61 displays inhibitory activity against LCK, with an IC50 of 24 nM.
Molekulargewicht:
386.45
CAS Nummer:
[875638-86-1]
Formel:
C23H22N4O2
Target-Kategorie:
Bcr-Abl|||MAPK|||Src
T212057
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