SMU-C68 is a highly selective small molecule agonist of the TLR1/2 heterodimer (EC50=0.009 µM). It activates the NF-kappaB and MAPK pathways, leading to the release of pro-inflammatory cytokines such as TNF-alpha and IL-1beta. SMU-C68 holds potential for cancer research applications.
Molekulargewicht:
411.54
CAS Nummer:
[2677039-75-5]
Formel:
C21H21N3O2S2
Target-Kategorie:
p38 MAPK|||NF-kappaB|||TLR
T212119
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