Rac1-IN-5 is a selective, reversible inhibitor of the RAC1 protein with a dissociation constant (KD) of 30 nM. It competes specifically with guanine nucleotides for binding to RAC proteins, effectively blocking RAC1 activity and RAC1-dependent cellular functions. In vivo, Rac1-IN-5 exhibits anti-tumor metastasis effects and can improve survival rates. This compound is applicable for research on aggressive cancers such as triple-negative breast cancer and colon cancer.
Molekulargewicht:
486.6
CAS Nummer:
[694515-65-6]
Formel:
C24H26N2O5S2
Target-Kategorie:
Ras|||Akt|||Acyltransferase
T212219
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