D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt Preis auf Anfrage

Produktübersicht

• Artikelname: D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt Preis auf Anfrage
• Artikelnummer: TGM-T212230
• Hersteller Artikelnummer: T212230
• Alternativnummer: TGM-T212230-10MG,TGM-T212230-50MG
• Hersteller: TargetMol
• Kategorie: Biochemikalien
• Alternative Synonym: Ins(1,3,4,5,6)P5 ammonium salt , 1,3,4,5,6-IP5 ammonium salt

Produktbeschreibung

D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) [Ins(1,3,4,5,6)P5 (ammonium salt)] is an isomer of inositol phosphate that functions as a small, soluble second messenger in cellular signaling. It can bind to the PH domain of Grp1 with a dissociation constant (Kd) of 590 nM. This compound inhibits the phosphorylation and kinase activity of Akt/PKB, leading to apoptosis in ovarian, lung, and breast cancer cells. Additionally, it exhibits anti-angiogenic activity in vitro, blocking capillary formation by HUVECs, and demonstrates antitumor effects in cancer xenograft models in nude mice.

Produkteigenschaften

• Target-Kategorie: Akt