CGP-74514 dihydrochloride is a highly selective inhibitor of cyclin-dependent kinase 1 (CDK1) with an IC50 of 25 nM. It effectively suppresses the activity of the CDK1/cyclin B complex, halting the cell cycle at the G2/M phase and inducing apoptosis in tumor cells. This compound shows potential for bladder cancer research.
Target-Kategorie:
Apoptosis|||CDK
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