Apoptosis inducer43 is an agent that promotes apoptosis. It has the capability to induce apoptosis in HCT116 cells, cause cell cycle arrest at the SubG0-G1 phase, trigger secondary necrosis, and increase the expression of caspase-3, p53, and Bax/Bcl-2. This compound also inhibits tumor growth in solid Ehrlich carcinoma (SEC) mouse models. Apoptosis inducer43 is applicable for research in colon cancer, leukemia, non-small cell lung cancer, and other cancers.
Target-Kategorie:
MDM-2/p53|||Caspase|||Bcl-2 Family|||Apoptosis
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