TL033 forms a component of an antibody-drug conjugate (ADC) as a drug-linker conjugate. It comprises a linker and a bioactive small molecule toxin. TL033 can be conjugated with the Sacituzumab antibody (anti-Trop-2) to synthesize BT001021, which exhibits anticancer activity against various cancers, including breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer.
Molekulargewicht:
1630.83
CAS Nummer:
[2356230-22-1]
Formel:
C76H103N13O23S2
Target-Kategorie:
Drug-Linker Conjugates for ADC
T212558
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