NLRP3 modulator 8, CAS [[3069891-88-6]] Preis auf Anfrage
Artikelnummer:
TGM-T212625
Hersteller Artikelnummer:
T212625
Alternativnummer:
TGM-T212625-10MG,TGM-T212625-50MG
Hersteller:
TargetMol
Kategorie:
Biochemikalien
NLRP3 modulator 8 (Compound 14) is an NLRP3 regulator that can significantly degrade the NEK7 protein (DC50 = 9 nM). In macrophages, NLRP3 modulator 8 can inhibit the activity of caspase-1 in a dose-dependent manner and reduce the release of IL-1beta triggered by the activation of the NLRP3 inflammasome. NLRP3 modulator 8 is applicable for the research of various diseases, including autoinflammatory and autoimmune diseases, neurodegenerative diseases, as well as cardiovascular and metabolic-related diseases, etc.
Molekulargewicht:
453.3
CAS Nummer:
[3069891-88-6]
Formel:
C20H19Cl2FN4O3
Target-Kategorie:
NOD
T212625
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