MKP10241 is an orally bioavailable GPR119 agonist that increases cAMP levels in GPR119-expressing cell lines with an EC50 of 3.7 nM. It significantly reduces blood glucose and glycated hemoglobin (HbA1c) levels in acute and chronic diabetic mouse models. It also exhibits favorable pharmacological activities in acute and chronic obesity models and MASH rodent models.
Molekulargewicht:
530.64
Reinheit:
99.79%
CAS Nummer:
[2137977-29-6]
Formel:
C24H27FN6O3S2
Target-Kategorie:
GPCR
T212859
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