AChE/BChE-IN-29 is an inhibitor of AChE/BChE. This compound exhibits balanced dual cholinesterase inhibitory activity, with an IC50 value of 2.1 µM against electric eel acetylcholinesterase (eeAChE) and 6.3 µM against horse serum butyrylcholinesterase (eqBChE). In an E. coli cell model, AChE/BChE-IN-29 effectively inhibits the aggregation of amyloid-beta (Abeta42) and tau protein. It is a useful agent for Alzheimers disease (AD) research.
