CDK2-IN-47 is a potent CDK2 inhibitor with an IC50 of 0.21 µM. It demonstrates strong anticancer activity against MCF-7, HCT-116, and MGC-803 cell lines. CDK2-IN-47 effectively induces G1 cell cycle arrest, retinoblastoma protein (Rb) dephosphorylation, and significant apoptosis. It is applicable for research on breast, colorectal, and gastric cancers.
Target-Kategorie:
CDK|||Apoptosis
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