GSTO1-IN-3 is a potent inhibitor of GSTO1-1, with an IC50 value of 0.11 µM, and exhibits selectivity towards GSTO2-2, GSTA1-1, and GSTP1-1 (IC50> 100 µM). It enhances the cytotoxic effects of Cisplatin on human breast cancer cells and inhibits IL-1beta release in mouse bone marrow-derived macrophages (BMDM). Additionally, GSTO1-IN-3 reduces inflammation in mice and is applicable for research related to breast cancer and inflammation.
Molekulargewicht:
251.75
CAS Nummer:
[158890-32-5]
Formel:
C14H18ClNO
Target-Kategorie:
Interleukin|||GST
T213767
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