Etidaligide sodium is a DNA repair inhibitor designed to prevent the repair of DNA damage in tumor cells. It also activates DNA-dependent protein kinase (DNA-PK) and poly (ADP-ribose) polymerase, enzymes that induce the phosphorylation of H2AX and the paralyzation of proteins.
Target-Kategorie:
Poly(ADP-ribose) Glycohydrolase (PARG)
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