mmu-miR-139-3p Antagomir is modified with a high-affinity cholesterol group. This miRNA antagomir inhibits the function of mature miRNA by specifically binding to it, thereby preventing its complementary pairing with target genes. Compared to miRNA inhibitors, miRNA antagomirs demonstrate greater stability and inhibitory effectiveness in animal studies, and they more easily penetrate cellular membranes and tissue gaps, concentrating in target cells.
Target-Kategorie:
MicroRNA
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