mmu-miR-139-3p Agomir is a specially chemically modified miRNA mimic, featuring methoxy modifications across the full length of the mature miRNA chain, with 2 and 4 thiophosphate linkages at the 5 and 3 ends, respectively, and a high-affinity cholesterol modification attached at the 3 end. This miRNA agomir mimics endogenous miRNA and enhances miRNA activity. Compared to regular mimics, miRNA agomirs show increased stability and inhibitory effects in animal experiments, and they more effectively penetrate cell membranes and tissue gaps to accumulate in target cells.
Target-Kategorie:
MicroRNA
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