2-Fluoropalmitic acid (2-Fluorohexadecanoic acid), a fatty acid containing fluorine atoms, serves as a potential therapeutic agent for glioblastoma (GBM) by inhibiting the viability, proliferation, and stem-like phenotype of glioma stem cells (GSCs), suppressing the expression of phosphorylated erk, CD133, and SOX-2, and leading to decreased MMP-2 activity and increased methylation of the MGMT promoter.
Molekulargewicht:
274.41
CAS Nummer:
[16518-94-8]
Formel:
C16H31FO2
Target-Kategorie:
MMP|||ERK|||Integrin|||Acyltransferase
T21842
T21842
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