AR-R17779 hydrochloride is a potent, selective full agonist of the nAChR, demonstrating K i values of 92 nM for the alpha7 subtype and 16,000 nM for the alpha4beta2 subtype. It is noted for its ability to enhance learning and memory in rats, suggesting potential therapeutic applications. Additionally, this compound exhibits anxiolytic properties and can mitigate inflammation by activating anti-inflammatory cholinergic (vagal) pathways [1] [2] [4].
Molekulargewicht:
218.68
CAS Nummer:
[178419-42-6]
Formel:
C9H15ClN2O2
Target-Kategorie:
Others|||AChR
T21857
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