MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC50 values of 30 nM and 16 nM, respectively. It exhibits greater selectivity for HDAC2/3 over other HDAC isomers and induces apoptosis in myeloid leukemic cells, indicating potential therapeutic use in leukemia and as an anti-stroke agent [1] [2].
Molekulargewicht:
383.44
CAS Nummer:
[1415340-63-4]
Formel:
C24H21N3O2
Target-Kategorie:
Others|||HDAC|||Apoptosis
T21898
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