ACHP (IKK-2 Inhibitor VIII) is a novel selective and potent IKK inhibitor with inhibitory effects on IKK-alpha and IKK-beta. ACHP has anti-HIV-1 activity and inhibits HIV-1 long terminal repeat (LTR)-driven gene expression through inhibition of NF-kappaB activation, inhibits TNF-alpha-induced NF-kappaB (p65) recruitment to the HIV-1 LTR, and inhibits TNF-alpha-induced NF-kappaB (p65) recruitment to the HIV-1 LTR. ACHKP has anti-HIV-1 activity and inhibits TNF-alpha-induced recruitment of NF-kappaB (p65) to the HIV-1 LTR.
Molekulargewicht:
364.44
Reinheit:
98.77%
CAS Nummer:
[406208-42-2]
Formel:
C21H24N4O2
Target-Kategorie:
IkappaB/IKK|||Apoptosis|||STAT
T22021
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