LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of beta-amyloid (Abeta), and can be used to study Alzheimers disease. It can be used to study Alzheimers disease.
Molekulargewicht:
438.58
Reinheit:
>99.99%
CAS Nummer:
[885104-09-6]
Formel:
C15H16BrCl3N4
Target-Kategorie:
GluR|||Beta Amyloid
T22204
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