2-Thio-UTP is a selective P2Y2 receptor (purinergic receptor) agonist (EC50 = 50 nM) capable of inhibiting calcification potential, alpha-smooth muscle actin expression, and pro-fibrotic gene expression in valvular interstitial cells (VICs). It may be employed in studies of calcific aortic valve stenosis (CAVS).
Molekulargewicht:
500.21
CAS Nummer:
[35763-29-2]
Formel:
C9H15N2O14P3S
Target-Kategorie:
Others|||P2Y Receptor
T22503
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