Pruvanserin hydrochloride (EMD 281014 HCl) is an inverse and selective 5-HT2A receptor antagonist with IC50 values of 0.35 nM and 1 nM for human and rat 5-HT2A receptors, respectively. Pruvanserin hydrochloride inhibits GTP-gamma-S accumulation and alleviates tactile allodynia in diabetic rats, making it suitable for studies on Parkinsons disease, insomnia, and schizophrenia.
Molekulargewicht:
412.89
Reinheit:
99.60%
CAS Nummer:
[443144-27-2]
Formel:
C22H22ClFN4O
Target-Kategorie:
5-HT Receptor
T22762
T22762
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