Proxyfan (Proxifan) is a high-affinity protean antagonist/agonist of histamine H3 receptors with a full spectrum of pharmacological activity ranging from full agonist to full inverse agonist(antagonist), depending on the competition between constitutively active and resting H3 receptors within a given tissue or brain region.Proxyfan acts as a neutral antagonist in the feeding-associated ventral medial nucleus of the hypothalamus, and as a agonist in the basolateral amygdala of the rat (BLA).
Molekulargewicht:
216.28
Reinheit:
99.68%
CAS Nummer:
[177708-09-7]
Formel:
C13H16N2O
Target-Kategorie:
Histamine Receptor
T23190
T23190
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