KDM2/7-IN-1 (TC-E 5002) is a selective small-molecule inhibitor of the KDM2/7 histone demethylase subfamily, exhibiting IC50 values of 0.2, 1.2, 6.8, 55, 83, >100, and >120 µM for KDM7A, KDM7B, KDM2A, KDM5A, KDM4C, KDM6A, and KDM4A, respectively. KDM2/7-IN-1 inhibits the proliferation of HeLa and KYSE-150 cancer cells in vitro, highlighting its utility in epigenetic and oncology research.
Molekulargewicht:
285.38
Reinheit:
99.87%
CAS Nummer:
[1453071-47-0]
Formel:
C15H27NO4
Target-Kategorie:
Histone Demethylase
T23429
T23429
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