Anxiolytic/nonsedative agent-1 (TCS 1205) is a potent and selective GABAA agonist. Anxiolytic/nonsedative agent-1 shows appreciable affinity for the BzR in bovine brain membranes with Kis of 14, 121, 239 nM for alpha1beta2gamma2, alpha2beta2gamma2, alpha5beta3gamma2, respectively. Anxiolytic/nonsedative agent-1 shows alpha2 selective efficacy in vitro and anxioselective effects in vivo.
Molekulargewicht:
337.33
Reinheit:
98.61%
CAS Nummer:
[355022-97-8]
Formel:
C18H15N3O4
Target-Kategorie:
GABA Receptor
T23445
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